{"id":3694,"date":"2022-11-13T16:36:50","date_gmt":"2022-11-13T16:36:50","guid":{"rendered":"https:\/\/idealmedical.co.za\/wp\/?post_type=product&p=3694"},"modified":"2025-08-05T03:38:58","modified_gmt":"2025-08-05T03:38:58","slug":"creatinine-pap-sl-clinical-chemistry-reagent-elitech","status":"publish","type":"product","link":"https:\/\/idealmedical.co.za\/wp\/product\/creatinine-pap-sl-clinical-chemistry-reagent-elitech\/","title":{"rendered":"Creatinine PAP SL Clinical Chemistry reagent; Elitech"},"content":{"rendered":"

INTENDED USE<\/strong><\/h3>\n

ELITech Clinical Systems CREATININE PAP SL is\u00a0intended for the quantitative in vitro <\/em>diagnostic determination of creatinine in human samples of serum, plasma and urine.<\/p>\n

CLINICAL<\/strong>\u00a0<\/strong>SIGNIFICANCE<\/strong>\u00a0<\/strong><\/h3>\n

Creatinine is the waste spontaneous product of creatine metabolism. It is an excellent marker of the renal function. The serum creatinine rate tends to remain constant. A high serum creatinine rate (associated to a high urea rate) corresponds to a decrease in renal glomerular filtration (FGR). The serum creatinine test is more reliable than the urea test. Indeed, the urea serum rate is affected by factors such as diet, dehydratation degree and protein metabolism (the serum creatinine rate is not influenced by these factors). The test of creatinine clearance can also be used to measure the FGR. In the case of renal transplantation, any increase in serum creatinine, as little as it may be, can reflect the rejection of the trans- plant. An increase of creatinine in serum and urine can be the sign of muscular necrosis.<\/p>\n

 <\/p>\n

METHOD<\/strong><\/p>\n

Enzymatic – Colorimetric – Kinetic.<\/p>\n

REAGENT<\/strong>\u00a0<\/strong>COMPOSITION<\/strong><\/h3>\n
Reagent 1 :<\/strong>\u00a0<\/strong>R1<\/strong><\/h5>\n

MOPS\u00a0buffer, pH 7.5<\/p>\n

EHSPT 0.4\u00a0mmol\/L<\/p>\n

Creatinase \u2265\u00a0 \u00a010\u00a0000 U\/L<\/p>\n

Sarcosine\u00a0Oxidase \u2265\u00a0\u00a0 3\u00a0500 U\/L<\/p>\n

Ascorbate\u00a0Oxidase \u2265\u00a0\u00a0 1\u00a0000 U\/L<\/p>\n

Reagent 2 :<\/strong>\u00a0<\/strong>R2<\/strong><\/h5>\n

MOPS\u00a0buffer, pH 7.5<\/p>\n

Amino-4-Antipyrine 2.95\u00a0mmol\/L<\/p>\n

Creatininase \u2265\u00a0150\u00a0000 U\/L<\/p>\n

Peroxidase \u2265\u00a0\u00a0 4\u00a0000 U\/L<\/p>\n

Sodium\u00a0azide < 0.1 %<\/p>\n

 <\/p>\n

MATERIALS<\/strong>\u00a0<\/strong>REQUIRED<\/strong>\u00a0<\/strong>BUT<\/strong>\u00a0<\/strong>NOT<\/strong>\u00a0<\/strong>PROVIDED<\/strong><\/h3>\n
    \n
  • CALI-0550\u00a0ELICAL\u00a02 4\u00a0x\u00a03\u00a0mL<\/li>\n
  • CONT-0060\u00a0ELITROL I 10\u00a0x\u00a05\u00a0mL<\/li>\n
  • CONT-0160\u00a0ELITROL II\u00a0 10\u00a0x\u00a05\u00a0mL<\/li>\n
  • Normal saline\u00a0solution\u00a0(NaCl\u00a09\u00a0g\/L)<\/li>\n
  • General\u00a0Laboratory\u00a0equipment.<\/li>\n
  • Do not use materials that are not required as indicated above.<\/li>\n<\/ul>\n

    DAMAGED<\/strong>\u00a0<\/strong>PACKAGING<\/strong><\/h3>\n

    Do not use the reagent if the damages of packaging might have an effect on the product performance (leak- ages, pierced vial).<\/p>\n

    SAMPLES<\/strong>\u00a0<\/strong><\/p>\n

    Specimen<\/strong><\/h5>\n
      \n
    • Serum or lithium heparinized plasma free from\u00a0hemolysis.<\/li>\n
    • 24h-Urine to be diluted 1:20 with saline solution NaCl\u00a09 g\/L. For users with Selectra Touch Pro software, pre-\u00a0dilution is performed automatically. Results take the\u00a0dilution\u00a0into\u00a0account.<\/li>\n
    • Do not\u00a0use other\u00a0specimens.<\/li>\n<\/ul>\n

       <\/p>\n

        \n
      • \n
        Warnings<\/strong>\u00a0<\/strong>and<\/strong>\u00a0<\/strong>precautions<\/strong><\/h5>\n<\/li>\n
      • According to Good Laboratory Practice, sampling should be performed prior to the administration of drugs. Sampling could lead to false results if performed during or immediately after the administration of some drugs.<\/li>\n
      • Do not\u00a0to\u00a0use acetic\u00a0acid\u00a0to stabilize\u00a0urine\u00a0samples.<\/li>\n<\/ul>\n
        Storage<\/strong>\u00a0<\/strong>and<\/strong>\u00a0<\/strong>stability<\/strong><\/h5>\n
          \n
        • Serum and plasma are stable for 7 days at 15-25 \u00b0C,\u00a07\u00a0days\u00a0at\u00a02-8\u00a0\u00b0C\u00a0and\u00a03\u00a0months\u00a0at\u00a0-20\u00a0\u00b0C.<\/li>\n
        • Urines are stable for 2 days at 15-25 \u00b0C, 6 days at\u00a02-8\u00a0\u00b0C\u00a0and\u00a06\u00a0months\u00a0at\u00a0-20\u00a0\u00b0C.<\/li>\n<\/ul>\n

           <\/p>\n

          REFERENCE<\/strong>\u00a0<\/strong>VALUES<\/strong>\u00a0<\/strong><\/p>\n

          Men\u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0Women<\/strong><\/h5>\n

          Serum,<\/em><\/u>\u00a0<\/em><\/u>plasma<\/em><\/u>\u00a0<\/em>:<\/p>\n

          0.72 – 1.18\u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a00.55 – 1.02 mg\/dL<\/p>\n

          64 – 104\u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 49 –\u00a0 \u00a090 \u03bcmol\/L<\/p>\n

           <\/p>\n

          Urine<\/em><\/u>: 14 –\u00a0 \u00a026\u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a011 – 20\u00a0\u00a0 \u00a0mg\/kg\/24h*<\/p>\n

          124 – 230\u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a097 – 177 \u03bcmol\/kg\/24h*<\/p>\n","protected":false},"excerpt":{"rendered":"

          INTENDED USE ELITech Clinical Systems CREATININE PAP SL is\u00a0intended for the quantitative in vitro diagnostic determination of creatinine in human samples of serum, plasma and urine. CLINICAL\u00a0SIGNIFICANCE\u00a0 Creatinine is the waste spontaneous product of creatine metabolism. It is an excellent marker of the renal function. The serum creatinine rate tends to remain constant. A high […]<\/p>\n","protected":false},"featured_media":3678,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[130],"product_tag":[],"class_list":{"0":"post-3694","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-elitech-clinical-chemistry","8":"first","9":"onbackorder","10":"shipping-taxable","11":"purchasable","12":"product-type-variable"},"yoast_head":"\nCreatinine PAP SL Clinical Chemistry Elitech - ideal solutions<\/title>\n<meta name=\"description\" content=\"ELITech Clinical Systems CREATININE PAP SL is\u00a0intended for the quantitative in vitro diagnostic determination of creatinine in human samples of serum, plasma and urine. We supply this reagent within South Africa, as well as to Botswana, Lesotho, Eswatini, Namibia, Zambia, Zimbabwe\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/idealmedical.co.za\/wp\/product\/creatinine-pap-sl-clinical-chemistry-reagent-elitech\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Creatinine PAP SL Clinical Chemistry Elitech - ideal solutions\" \/>\n<meta property=\"og:description\" content=\"ELITech Clinical Systems CREATININE PAP SL is\u00a0intended for the quantitative in vitro diagnostic determination of creatinine in human samples of serum, plasma and urine. 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