{"id":6705,"date":"2024-11-04T17:33:18","date_gmt":"2024-11-04T17:33:18","guid":{"rendered":"https:\/\/idealmedical.co.za\/wp\/?post_type=product&#038;p=6705"},"modified":"2024-11-04T17:35:49","modified_gmt":"2024-11-04T17:35:49","slug":"ck-nac-sl-clinical-chemistry-reagent-elitech","status":"publish","type":"product","link":"https:\/\/idealmedical.co.za\/wp\/product\/ck-nac-sl-clinical-chemistry-reagent-elitech\/","title":{"rendered":"CK NAC SL Clinical Chemistry Reagent, Elitech"},"content":{"rendered":"<p><strong>INTENDED USE<\/strong><br \/>\nELITech Clinical Systems CK NAC SL is an in vitro diagnostic reagent intended for the quantitative determination of creatine kinase (CK) in human serum and plasma samples on analyzers or semi-automatic analyzers.<br \/>\nThis in vitro diagnostic device is for professional use only.<\/p>\n<p><strong>CLINICAL SIGNIFICANCE<\/strong><br \/>\nCreatine kinase (CK) exists in 3 cytoplasmic forms:<br \/>\nCK-MM (dominant isoenzyme in striated and cardiac muscles), CK MB (mostly in cardiac muscle), and CKBB (only isoenzyme in brain).<br \/>\nEnzymatic activity of total creatine kinase is increased during muscle damage such as Duchenne dystrophy,<br \/>\nrhabdomyolysis, inflammatory diseases, myocardia infarction and trauma.<br \/>\nCertain antipsychotic drugs (olanzapine and quetiapine), and in some cases hypothyroidism, also trigger<br \/>\nelevated total CK activity.<br \/>\nDetermination of total CK is used to help diagnose and to follow-up conditions associated with muscle<br \/>\ndamage.<\/p>\n<p><strong>LIMITATION OF USE<\/strong><br \/>\nThe quantitative assay of creatine kinase (CK) alone cannot be used to diagnose a disease or a specific<br \/>\npathology.<br \/>\nThe results must be interpreted in conjunction with other diagnostic test results, clinical findings and the<br \/>\npatient\u2019s medical history<\/p>\n<p><strong>COMPOSITION<\/strong><br \/>\nReagent 1 : R1<br \/>\nImidazole buffer, pH 6.1 (20 \u00b0C)<br \/>\nD-Glucose 25 mmol\/L<br \/>\nNADP 2.5 mmol\/L<br \/>\nHexokinase \u2265 6 800 U\/L<br \/>\nSodium azide &lt; 0.1 % (w\/w)<\/p>\n<p>Reagent 2 : R2<br \/>\nImidazole buffer, pH 8.9 (20 \u00b0C)<br \/>\nCreatine phosphate 250 mmol\/L<br \/>\nADP 15.2 mmol\/L<br \/>\nG-6-PDH \u2265 8 800 U\/L<br \/>\nSodium azide &lt; 0.1 % (w\/w)<br \/>\nAlso contains magnesium salts, N-acetyl cysteine,E DTA, diadenosine pentaphosphate and AMP for optimal performance.<\/p>\n<p><strong>MATERIALS REQUIRED BUT NOT PROVIDED<\/strong><br \/>\n&#8211; CALI-0550 ELICAL 2<br \/>\n&#8211; CONT-0060 ELITROL I<br \/>\n&#8211; CONT-0160 ELITROL II<br \/>\n&#8211; Normal saline solution (NaCl 9 g\/L).<br \/>\n&#8211; Analyzers or semi-automatic analyzers.<br \/>\n&#8211; General Laboratory equipment (e.g. pipette).<br \/>\n&#8211; Do not use materials that are not required as indicated above<\/p>\n","protected":false},"excerpt":{"rendered":"<p>INTENDED USE ELITech Clinical Systems CK NAC SL is an in vitro diagnostic reagent intended for the quantitative determination of creatine kinase (CK) in human serum and plasma samples on analyzers or semi-automatic analyzers. This in vitro diagnostic device is for professional use only. CLINICAL SIGNIFICANCE Creatine kinase (CK) exists in 3 cytoplasmic forms: CK-MM [&hellip;]<\/p>\n","protected":false},"featured_media":6562,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[130],"product_tag":[],"class_list":{"0":"post-6705","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-elitech-clinical-chemistry","8":"first","9":"onbackorder","10":"shipping-taxable","11":"purchasable","12":"product-type-variable"},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.6 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>CK NAC SL Clinical Chemistry Reagent, Elitech - ideal solutions<\/title>\n<meta name=\"description\" content=\"ELITech Clinical Systems CK NAC SL is an in vitro diagnostic reagent intended for the quantitative determination of creatine kinase (CK) in human serum and plasma samples on analyzers or semi-automatic analyzers. We supply this reagent within South Africa, as well as to Botswana, Lesotho, Eswatini, Namibia, Zambia, Zimbabwe\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/idealmedical.co.za\/wp\/product\/ck-nac-sl-clinical-chemistry-reagent-elitech\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"CK NAC SL Clinical Chemistry Reagent, Elitech - ideal solutions\" \/>\n<meta property=\"og:description\" content=\"ELITech Clinical Systems CK NAC SL is an in vitro diagnostic reagent intended for the quantitative determination of creatine kinase (CK) in human serum and plasma samples on analyzers or semi-automatic analyzers. 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