Copper(II) sulfate pentahydrate ACS reagent, ≥98.0%

Copper(II) sulfate pentahydrate is a Lewis acid catalyst commonly used to promote acid-catalyzed organic transformations. It can also act as an effective redox catalyst in combination with other mixed oxidizing agents.

Copper(II) sulfate pentahydrate can be used as a catalyst:

• In acetylation of alcohols and phenols in the presence of acetic anhydride.
• To synthesize various ynamides via intramolecular coupling of amides with alkynyl bromides.

It can also be used as a template in the synthesis of copper(II) ion-imprinted polymers using vinylpyridine and methacrylic acid as functional monomers. This polymer is used to quantify Cu²⁺ ion by using flame atomic absorption spectroscopy.

CuSO₄.5H₂O is an inexpensive, safe catalyst to be used in various organic transformations. It can also be recovered and reused in another reaction.