Iodine, ACS reagent, ≥99.8%, solid

Iodine exhibits exceptionally high dielectric polarization in various solvents (dioxane, isobutylene, p-xylene and benzene).

Catalyst for synthesis of esters by condensation of carboxylic acids with alcohols or transfesterification.

Iodine has been used for the easy visualization of 9-bromononanoic acid, allyl ester by thin layer chromatography (TLC). It has also been used for the preparation of oxidation solution, required for the synthesis of oligodeoxynucleotides bearing 3′-terminal phosphorothioate.

Iodine may be used to catalyze:

• Synthesis of 5-(4-nitrophenyl)-10,15,20-triphenylporphyrin.
• Oxidative C-H bond amination of saturated hydrocarbons.
• Protection of amines with benzyloxycarbonyl (Cbz) group.
• Direct oxidative coupling/annulation of β-keto esters or 2-pyridinyl-β-esters with alkenes to form dihydrofurans and indolizine, respectively.
• Thiocyanation of aromatic systems to form aryl thiocyanates.
• Esterification of cellulose with acetic anhydride to form cellulose triacetate.