Description
Synonym: Phenylhydrazinium chloride
Linear Formula: C6H5NHNH2 · HCl
Application
Phenylhydrazine hydrochloride is used in the examination of tyrosine phosphorylation of Janus protein tyrosine kinase (JAKs) in the EPO-responsive normal erythroblastoid cells of anemic mice.
Biochem/physiol Actions
Phenylhydrazine hydrochloride causes acute hemolysis when injected intraperitoneally in to wild-type and Hp and Hx single-null mice. It suppresses the horseradish peroxide (HRP) residual activity in tissue sections of animals.
Preparation Note
50 gm of Phenylhydrazine hydrochloride dissolves in 1 mL of water to yield a clear, very faint yellow solution.
PROPERTIES
Assay
≥99%
form
solid
mp
250-254 °C (dec.) (lit.)
solubility
H2O: soluble 50 mg/mL
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