Description
Synonym(s): D-(−)-threo-2,2-Dichloro-N-[β-hydroxy-α-(hydroxymethyl)-β-(4-nitrophenyl)ethyl]acetamide, D-(−)-threo-2-Dichloroacetamido-1-(4-nitrophenyl)-1,3-propanediol, D-threo-2,2-Dichloro-N-[β-hydroxy-α-(hydroxymethyl)-4-nitrophenethyl]acetamide, Chloromycetin
Linear Formula: Cl2CHCONHCH(CH2OH)CH(OH)C6H4NO2
General description
Chemical structure: phenicole
Application
Chloramphenicol is a synthetic antibiotic, isolated from strains of Streptomyces venezuelae. It is often used for bacterial selection in molecular biology applications at 10-20μg/mL and as a selection agent for transformed cells containing chloramphenicol reistance genes.
Chloramphenicol has been used as a bacteriostatic non potent antibiotic. It has been used for the selection/growth of positive bacterial cells.
Chloramphenicol has been used as a bacteriostatic non potent antibiotic. It has been used for the selection/growth of positive bacterial cells.
PROPERTIES
assay
≥98% (HPLC)
form
powder or crystals
pKa
5.5
mp
148-150 °C (lit.)
antibiotic activity spectrum
Gram-negative bacteria
Gram-positive bacteria
mycobacteria
mycoplasma
Mode of action
protein synthesis | interferes
storage temp.
room temp
![Propan-2-ol uniLAB® [2.5 Litres]](https://idealmedical.co.za/wp/wp-content/uploads/2020/08/826-Propan-2-ol-200x200.jpg)
![Universal indicator solution uniLAB, Merck [100ml]](https://idealmedical.co.za/wp/wp-content/uploads/2020/08/276-pH-indicator-soln-300x300.jpg)
Reviews
There are no reviews yet.