Description
Synonyms: Acid Yellow 73, D&C;Yellow No. 8, NaFl, NaFluo, Sodium fluorescein, Uranine
Empirical Formula (Hill Notation): C20H10Na2O5
Molecular Weight: 376.27
General description
Fluorescein is a xanthene dye and is a common labeling agent in biology.
Application
Fluorescein sodium salt has been used as a solute to study microvessel permeability. It has been used as a test molecule to study blood barrier penetration.
Water soluble fluorescent dye used in permeability and vascular perfusion studies due to its small molecular radius. Sodium fluorescein is used as a fluorescent tracer to study blood-brain barrier (BBB) and blood-spinal cord barrier (BSCB) permeability in rodent models.The dye was used as a probe substrate in the study of organic anion transporting polypeptide (OATP) mediated drug transport in hepatocytes. Sodium fluorescein was also used to monitor in situ solute transportation into bone through fluorescence recovery after photobleaching (FRAP).
Properties
Product Name
Fluorescein sodium salt, used as fluorescent tracer
Pack Size
500g
form
powder
technique(s)
titration: suitable
pH
8.3 (20 °C, 10 g/L)
mp
>300 °C
solubility
H2O: 1 mg/mL
density
0.78 g/cm3 at 29.6 °C (85.3 °F at 699.7 hPa)
fluorescence
λex 460 nm; λem 515 nm(lit.)
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
room temp
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