Sodium citrate tribasic dihydrate

Sodium citrate tribasic dihydrate can be used as a catalyst to synthesize:

• Fused O– and N-heterocyclic derivatives via multicomponent Knoevenagel-cyclocondensation of isatin/aldehyde/ acenaphthylene-1,2-dione, malononitrile, and various C−H activated acids.
• Chromeno[3′,4′:5,6]pyrano[2,3-d]pyrimidines by the condensation reaction of 4-hydroxycoumarin, aromatic aldehydes, and barbituric acid/thiobarbituric acid.

It can also be used as:
A reducing agent to synthesize metal nanoparticles via sol-gel method using corresponding metal salt precursors.
A controlling agent in the synthesis of single-crystal of coordination polymer [Co(H₂O)₂Ni(CN)₄ 4H₂O].