Sodium hypochlorite solution 5%

Sodium hypochlorite (NaOCl) is a commonly used reagent in organic synthesis for many oxidation and chlorination reactions.

Sodium hypochlorite solution can be used as an oxidizing agent for the oxidation of:

• Primary alcohols to aldehydes or carboxylic acids and secondary alcohols to ketones.
• Aryl aldehydes to the corresponding acids in the presence of a phase-transfer catalyst.
• Ethers to esters by careful pH control (pH range of 8–9.5),

It can also be used as a reagent in the:

• Epoxidation of enones and polycyclic arenes.
• Oxidative degradation reaction
• N-Chlorination of primary and secondary amines
• Enantioselective epoxidation of α, β-unsaturated ketones
• Asymmetric dihydroxylation of olefins in the presence of an osmium catalyst
• Chlorination of allylic carbons in the presence of CeCl₃

• Readily available reagent
• Easily handled oxidizing agent
• No phase-transfer catalyst is necessary for the oxidation of substrates in the pH range 10–11
• Simplified waste disposal and lower toxicity